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Evolocumab

Product Name
Evolocumab
CAS No.
1256937-27-5
Chemical Name
Evolocumab
Synonyms
AMG 145;Evolocumab;Evolocumab(anti-PCSK9);Research Grade Evolocumab(DHJ24002);AMG-145,Ser/Thr Protease,Repatha,AMG 145,inhibit,atherosclerotic cardiovascular disease,Serine endopeptidases,PCSK9,Evolocumab,AMG145,Threonine proteases,hypercholesterolemia,LDLR,Inhibitor,Serine proteases
CBNumber
CB72744219
Formula Weight
0
MOL File
Mol file
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Evolocumab Property

storage temp. 
Store at 4°C, protect from light
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Safety

Hazardous Substances Data
1256937-27-5(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BE165589
Product name
Evolocumab - solution - 5 mg/ml
Packaging
1mg
Price
$550
Updated
2021/12/16
DC Chemicals
Product number
013344
Product name
Evolocumab
Packaging
002
Price
$750
Updated
2021/12/16
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Evolocumab Chemical Properties,Usage,Production

Clinical Use

IgG2 monoclonal antibody:
Treatment of hypercholesterolaemia, mixed dyslipidaemia and homozygous familial hypercholesterolaemia

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: avoid with clozapine - increased risk
of agranulocytosis. Vaccines: avoid concomitant use with live vaccines.

Metabolism

Evolocumab is composed of amino acids and carbohydrates as native immunoglobulin and is unlikely to be eliminated via hepatic metabolic mechanisms. Its metabolism and elimination are expected to follow the immunoglobulin clearance pathways, resulting in degradation to small peptides and individual amino acids.

Evolocumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Evolocumab Suppliers

Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354
Email
support@targetmol.com
Country
United States
ProdList
19973
Advantage
58
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9926
Advantage
65

1256937-27-5, EvolocumabRelated Search:


  • Evolocumab
  • AMG 145
  • Research Grade Evolocumab(DHJ24002)
  • AMG-145,Ser/Thr Protease,Repatha,AMG 145,inhibit,atherosclerotic cardiovascular disease,Serine endopeptidases,PCSK9,Evolocumab,AMG145,Threonine proteases,hypercholesterolemia,LDLR,Inhibitor,Serine proteases
  • Evolocumab(anti-PCSK9)
  • 1256937-27-5